Biognosys’ mass spectrometry-based Digital Proteome is one of the most comprehensive resources available for tissue specific protein expression, covering over 20 healthy and diseased tissue types from both human and preclinical species. Continuously expanded with new tissues and species, the dataset serves as a robust reference for biomarker discovery, translational research, and tissue-targeted drug development.
Survey tissue-wide target and off-target protein expression profiles to inform safety and toxicological risk assessment.
Identify tissue-specific proteoforms, including isoforms, post-translational modifications, mutations, and non-canonical proteins.
Support translational research with consistent and comparable proteomics data across human and preclinical species.
Identify peptides suitable for absolute quantification in customizable targeted protein panels.
Estimate baseline expression levels of therapeutic targets across tissues and species.
Use dataset as robust input for machine learning and predictive modeling.
Deep fractionation DDA-MS profiling identified over 5 million modified peptides, mapping to 17,944 (human tissues), 13,562 (human blood cells), 17,800 (mouse), 21,665 (rat), 20086 (minipig), 19,660 (dog) and 17,416 (monkey) protein groups, including protein-level evidence for previously unconfirmed or predicted sequences.
Using single-shot DIA-MS over 1 million peptides were quantified, covering 11,042 (human tissues), 6,366 (human blood cells), 12,822 (mouse), 14,099 (rat), 14,494 (minipig), 13,420 (dog) and 14,170 (monkey) protein groups.
Broad coverage of biological pathways, drug targets, and tissue-specific isoforms supporting diverse applications from mechanism-of-action studies to therapeutic target validation.
One-time delivery of raw files and curated protein tables (DDA and DIA) for each species and tissue module, ready for immediate integration into your research workflow.
We offer the creation of customer specific Digital Proteomes as CRO service project. Reach out to our experts to discuss your specific needs.
The purchase of this data will provide non-exclusive rights to the data’s use. MS raw data will be transferred to AWS S3 bucket provided by the purchaser account or an alternative method.
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